Syk

基本解释

Flag-tagged Syk(L) domains SH2, KD, and IDB(L) were transfected into HEK293 cells, respectively, and their interaction with HDAC1 was detected.
构建带有FLAG标志的Syk(L)各个功能域质粒,并将其转染入HEK293细胞中,采用免疫沉淀方法检测HDAC1与Syk(L)各个功能域之间的结合。
The IDB domain of Syk(L)has complete nuclear translocalization function,which is able to transport cytoplasm protein GFP into nucleus.
Syk(L)的IDB域具有完整的核移位功能,能将融合的胞浆蛋白GFP转移到细胞核内;
AIM:To evaluate the relationship between spleen tyrosine k in ase(Syk)and the biological charcter of keloid fi broblasts(KFB)based on the research of signal transduction of keloid fibro blasts.
目的:通过瘢痕疙瘩成纤维细胞(KeloidFibroblasts,KFB)信号传递的研究,探讨脾酪氨酸激酶(SpleenTyrosineKinase,Syk)与KFB生物学性状改变的关系。
BACKGROUND & OBJECTIVE: Full-length form of spleen tyrosine kinase [Syk(L)] is a tumor suppressor gene in breast cancer, which may translocate into cell nucleus and act as a transcriptional repressor.
背景与目的:全长型脾脏酪氨酸激酶[full-length form of spleen tyrosine kinase,Syk(L)]在乳腺癌中具有抑癌功能,可移位到细胞核内,作为转录抑制因子调节基因的转录。
Relationship between hypermethylation of Syk gene in promoter and oncogenesis, metastasis of gastric carcinoma
候选抑癌基因Syk启动子甲基化与胃癌转移相关