crippling

基本解释

Another crippling characteristic of thin clients is that nearly all user interaction is at the page level.
瘦用户机的另一个缺陷就是几乎所有的用户交互都发生在页面级别。
At 22, being taken care of is a crippling thing. You’ve spent four years at college learning how to live on your own, and suddenly that disappears.
在22岁的时候还被人照顾是一件很伤人的事，你已经在学校花了四年的时间学习怎么独立生存，但忽然之间一切都消失了。
Do you suffer from crippling anxiety because you’re the only one in the room who can’t manage the simple act of wearing earbuds?
当你发现整个房间里就你一个人没法完成把耳塞塞进耳朵里这样简单的动作，你是否经历了难以名状的焦虑？

"And so,this isn't about crippling law enforcement or making it so criminals can get away with crime with impunity.
And so it's not, perhaps, crippling if this is the conclusion we reach, but at the same time it's not the only possible conclusion.
因此，如果这就是我们的结论，也没有太大关系，但同时要知道这不是惟一可能的结论。
耶鲁公开课 - 文学理论导论课程节选
So, polio--the disease caused by polio can be a paralytic disease, crippling, and in some cases can lead to death if the disease progresses in certain ways.
小儿麻痹症便是由脊髓灰质炎病毒引起的,如果脊髓灰质炎发展到一定程度,患者不仅会瘫痪或者残疾,一些病例甚至可能死亡
耶鲁公开课 - 生物医学工程探索课程节选

Levine the Court gave a bright green light to personal injury lawyers filing crippling lawsuits against pharmaceutical companies.
FORBES: Supremely Destructive Stupidity

A crippling illness or disability is one that severely damages your health or your body.
If you say that an action, policy, or situation has a crippling effect on something, you mean it has a very serious, harmful effect.