Bonta

基本解释

Competing ELISA showed that recombinant ScFv could compete with antiserum to specific hind BoNTa.
竞争活性测定结果表明，重组抗毒素在体外具有良好的活性，可竞争肉毒抗毒素马血清与毒素的特异结合。
Human ScFv against botulinum neurotoxin serotype A(BoNTa) was modified by fusing human IgG1 Fc to C terminal of ScFv. ScFv-Fc fusion protein was expressed at high level over 30% of total host cell proteins in E. coli.
以获得的抗A型肉毒毒素单链抗体为模板,进行融合改构,将人IgG1的Fc片段连接到ScFv的C端,在大肠杆菌中实现抗体融合蛋白ScFv-Fc的表达,表达量30%25以上,蛋白以包含体形式存在,经过体外变复性的抗体融合蛋白ScFv-Fc,进行Prote in G Sepharose柱亲和层析纯化,纯度达90%25~95%25。
Bontaş
邦塔什
abstract ： To evaluate the effect of intraprostatic injection of botulinum toxin A (BoNTA) on prostate volume and refractory urinary retention in patients with benign prostatic enlargement.
评论：作者研究于良性摄护腺肥大患者接受摄护腺内注射A型肉毒杆菌素，对于摄护腺体积与排尿改善的效果。