frequency locus

基本解释

Methods A simple, rapid and sensitive poly-nuclear cell assay was used to investigate the frequency of HPRT locus mutation.
方法采用多核细胞法研究肿瘤患者外周血淋巴细胞HPRT基因位点的突变频率，并与正常人群进行对比。
Conclusion The frequency of HPRT locus mutation may be expected to be a potential biological indicator for cancer risk assessment.
不同种类癌症患者外周血HPRT基因突变频率无显著差异。结论HPRT基因突变频率分析可作为患癌风险评估的生物学标志。
Conclusion The mutant frequency at HPRT locus can be served as one of the biomarkers for detecting genetic damage of human exposure to environmental and occupational mutagens.
结论体细胞HPRT基因位点突变频率可作为各种有害因素对机体遗传损伤的生物标识物之一。